Promoter elements in the aflatoxin pathway polyketide synthase gene.

نویسندگان

  • Kenneth C Ehrlich
  • Beverly G Montalbano
  • Jeffrey W Cary
  • Peter J Cotty
چکیده

PksA catalyzes the formation of the polyketide backbone necessary for aflatoxin biosynthesis. Based on reporter assays and sequence comparisons of the nor1-pksA intergenic region in different aflatoxin-producing Aspergillus species, cis-acting elements for the aflatoxin pathway-specific regulatory protein, AflR, and the global-acting regulatory proteins BrlA and PacC are involved in pksA promoter activity.

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عنوان ژورنال:
  • Biochimica et biophysica acta

دوره 1576 1-2  شماره 

صفحات  -

تاریخ انتشار 2002